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Archive for the ‘Biomarkers’ Category

MEDICAL NEWS TODAY: The boom in cancer biomarker investments over the past 25 years has not translated into major clinical success. READ MORE> The reasons for biomarker failures include problems with study design and interpretation, as well as statistical deficiencies, according to an article in The Journal of the National Cancer Institute. …if the biomarker [...]

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URO TODAY: Emerging urine tests should help in both early diagnosis of prostate cancer and identifying aggressive tumors for radical treatment.

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SCIENCE-CENTRIC.COM: A study of prostate risk factors in Japanese men seems to reinforce the idea that discovered variants are often simply population-specific markers that need far more study to confirm as functional culprits.

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URO TODAY: Australian researchers have identified a novel transcription factor in metastatic prostate cancer designated IV07, which appears to be involved in the regulation and co-ordination of multiple cancer promoting pathways.

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JUNE 25: NEW PROSTATE CANCER INFOLINK: “We need to start really focusing on whether this or that genetic variation has any prognostic impact on prostate cancer risk before we waste a lot of money chasing associations that have minimal likelihood of prognostic value,” writes Mike Scott.

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JUNE 21: URO TODAY: The human genome project and high throughput gene expression profiling has recently yielded several promising molecular biomarkers for prostate cancer detection beyond PSA or PSA modifications.

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JUNE 19: DRUGS.COM: A new marker for advanced prostate cancer and metastasis, or spread, of the disease has been identified by US researchers.

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JUNE 13: URO TODAY: WAVE3 is pivotal in controlling the invasiveness of prostate cancer cells, according to a new study at Cardiff University School of Medicine in the UK.

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JUNE 6: URO TODAY: Two ongoing, randomized controlled trials are examining whether screening reduces the risk of prostate cancer-related mortality, and the results of these studies are expected soon.

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JUNE 6: WEB MD: A blood test that characterizes each prostate tumor by its unique genetic fingerprint may help pinpoint which men actually have prostate cancer, researchers say.

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