URO TODAY: Researchers have discovered that prostate tumours in mice can cause immune cells known as CD8+ T cells to change to cells that suppress immune responses. READ MORE>
This finding, by researchers at the US National Cancer Institute, has important implications for the design of immune-based therapies for cancer.
Future work by this team will focus on defining the mechanisms by which gain their suppressive functions.
“This will enhance our ability to generate more effective anti-tumor T cell responses in mice, which then might be translated to human.”