URO TODAY: One in five men have a DNA variation that increases the risk of prostate cancer recurring after surgery, even though other factors (early diagnosis, low aggression, etc) may be in their favour. READ MORE> and HERE>
Department of Radiation Oncology, Vanderbilt University, Nashville, US:
The A/G genotype of rs10895304 is predictive of decreased recurrence-free survival in patients with clinically localised prostate cancer.
Our data suggest that for this subset of patients, prostatectomy alone may not be adequate for local control.
This is a novel and relevant marker that should be evaluated for improved risk stratification of patients who may be candidates for adjuvant radiation therapy to improve local control.