Archive for the ‘Bone cancer’ Category

URO TODAY: An experiment that combines a standard advanced prostate cancer drug treatment with a vaccine to assist the immune system has just begun in the US. READ MORE>

Looking to harness the body’s own immune system to target prostate cancer that has spread to the bones (metastatic) and is unresponsive to standard treatment, investigators have just launched a clinical trial combining vaccine and radiation drug therapy.

The goal is to see if disease progression will be further delayed by adding two different experimental injections to the standard treatment.

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IN-SCIENCES.ORG: Fucosylations – structures on the surface of prostate cancer cells – trigger prostate cancer cell adhesion inside a blood vessel wall in bone tissue, greatly increasing the prospect of prostate cancer cells metastasizing to bone. READ MORE>

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JohnMary1JULY 10: PROSTABLOG NZ: “It’s sad that medical professionals in NZ are so scared of possible side effects from a treatment like Ketoconazole, that they refuse to even acknowledge it, even if it has been proven to be effective overseas.”

These words were written today by Mary – a Kiwi whose partner has advanced prostate cancer – as she describes the frustration of being unable to persuade NZ doctors to move outside what seem to her to be inflexible approaches to treatment.

“I produced prostate cancer digests from people I know who have had large drops in PSA on Keto, but I was told I know only a few people and trials showing side effects have been done on thousands,” she says.

“When I said I would like to see the papers on this, I was told I was not a doctor…and to this I respond “no, but I am the partner of a man with advanced cancer.”

READ the second chapter of Mary’s struggle to save her man.

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JUNE 30: URO TODAY: In selected patients with prostate cancer metastases to the spine, aggressive surgical decompression and spinal reconstruction is a useful treatment option. The results show that on average, neurological outcome is improved and use of analgesics is reduced. Gleason score, metastatic burden, and degree of spinal canal compression may be associated with survival following surgery, and thus should be considered carefully prior to opting for surgical management. READ MORE>

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JUNE 16: URO TODAY: Preventive measures against adverse effects and careful assessment of a patient’s baseline health status should be considered when using androgen deprivation therapy, say researchers in Texas. They found ADT is associated with an increased risk of skeletal fracture, incident diabetes, and cardiovascular-related mortality, although the absolute risk of these events is low. READ MORE>

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JUNE 13: CANCER CONSULTANTS.COM: Researchers report that treatment with human antibody denosumab significantly reduces the incidence of bone fracture in prostate cancer patients on androgen deprivation therapy. READ MORE>

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MAY 30: PROSTABLOG NZ:  The partner of a NZ man with advancing prostate cancer says the public health system can’t test him for bone deterioration for at least year.  FULL STORY HERE>

Meantime, he goes untreated for osteoporosis, a well-known side effect of treatment he has been receiving for two years for his prostate cancer, which is now showing signs of spreading.

He was diagnosed in 2007 and hormone therapy since then kept signs of cancer spread in check.

But hormone therapy (as well as possibly causing bone deterioration) works for only a limited time, and now his prostate specific antigen levels are rapidly increasing, a sign the treatment is no longer effective.

The couple was told by his public health doctor a bone test could not be done for at least a year because 0f the long waiting list in the public health system.

Despite not being wealthy, they have abandoned the public system in desperation to get help from a private specialist.

In her story – published in full on the page titled John and Mary’s prostate saga – she tells of her quest for empowerment in dealing with the medical system.

Recently, she joined the US-based New Prostate Cancer Info-Link social network, where the expert sitemaster has offered some advice.

While he says the doctors were undoubtedly doing their best, one conclusion to be drawn is NZ is way behind the US when it comes to treating prostate cancer.

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