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Posts Tagged ‘biochemical failure’

NEW PROSTATE CANCER INFOLINK:  How often after prostate surgery should a “low risk” patient have his PSA tested to check if the cancer is coming back? READ MORE>

Tollefson et al. conclude that,  in low-risk patients, the risk of biochemical failure is inversely proportional to time for which the PSA is undetectable after radical prostatectomy.

They go on to suggest that taking PSA levels every two years should be sufficient to identify the majority of low-risk patients who experience biochemical progression.

The “New” Prostate Cancer InfoLink would certainly agree that annual PSA testing is probably unnecessary in the majority of patients who are treated surgically for low-risk disease if their PSA is undetectable after surgery.

However, the key question is how long should annual PSA testing be carried out before the patient can be switched to testing every two (or perhaps even every three) years.

Based on this paper, it would seem likely that even low-risk patients should all receive at least annual testing for three years after surgery.

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URO TODAY: Brachytherapy involving permanent insertion of radioactive seeds is giving excellent long-term results with prostate cancer patients, regardless of disease severity, a 12-year study has found. READ MORE>

At 12 years, biochemical failure and cause-specific mortality were 1.8% and 0.2%, 5.1% and 2.1%, and 10.4% and 7.1% for Gleason scores 5 to 6 and 7 and >/=8, respectively.

These results are echoed by a Canadian study. READ MORE>

And a Serbian study adds further similar information. READ MORE>

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URO TODAY: High-dose radiotherapy is superior to conventional-dose radiotherapy in preventing biochemical failure, according to new research, suggesting that this should be offered as a treatment for all patients, regardless of their risk status. READ MORE>

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URO TODAY: A better definition of biochemical failure, improved imaging techniques, and accurate specimen mapping are needed to diagnose the return of cancer more quickly after treatment like radiotherapy. READ MORE>

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MAY 16: NEW PROSTATE CANCER INFO-LINK:  The results of at least 15 prostate cancer-related studies will be presented at the upcoming annual meeting of the American Society for Clinical Oncology in Orlando, Florida, at the end of May. READ MORE>

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