Posts Tagged ‘Gleason grade’

NEW PROSTATE CANCER INFOLINK: Jonathon Epstein, MD, at Johns Hopkins is widely considered to be one of the pre-eminent prostate cancer pathologists in the world today, so it is worth listening when he says that the Gleason grading system needs revision. READ MORE>

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URO TODAY: Fragmentation of a prostate biopsy core can potentially distort analysis of the cancer’s extent and aggressiveness, a new study has confirmed. READ MORE>

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A big, big day today – my first blood test since surgery in late March shows UNDETECTABLE levels of prostate-specific antigen.

It was not unexpected. When the prostate has been removed and found not to have cancer cells near its margins, and the tumour is low-grade (Gleason 6), and there was no sign of anything in its immediate vicinity being cancerous, well the PSA will usually be nil.

However, it’s one thing to “know” this before the test, to understand this indeed is the likely outcome of the first PSA, because that’s what all the research, etc, says will be the case – but it’s quite another to actually get the result that confirms it.  READ MORE>

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JULY 31: URO TODAY: What’s the most accurate way your specialist can predict your fate when you first learn you have prostate cancer? Using something called a nomogram, according to latest analysis. READ MORE>

Researchers at the University of Montreal Health Center reviewed tools available to clinicians involved in treatment decisions in newly diagnosed prostate cancer and examined their accuracy to provide individual life expectancy.

“…nomograms provide the most accurate health-adjusted life expectancy prognostication,” they conclude.

What’s a nomogram?

It’s a calculation that gives an estimate – in this case, of life expectancy – after known information is fed into it.

The Memorial Sloan Kettering Cancer Center in the US has one for prostate cancer on its website. Anyone who knows the results of PSA, biopsy and Gleason grade can use it: CLICK HERE>

Here’s an example:


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JUNE 27: NEW PROSTATE CANCER INFOLINK: The predominance of Gleason pattern 4 in Gleason 7 cancers is a critically important prognostic factor. READ MORE>

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