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Posts Tagged ‘immune system’

URO TODAY: An experiment that combines a standard advanced prostate cancer drug treatment with a vaccine to assist the immune system has just begun in the US. READ MORE>

Looking to harness the body’s own immune system to target prostate cancer that has spread to the bones (metastatic) and is unresponsive to standard treatment, investigators have just launched a clinical trial combining vaccine and radiation drug therapy.

The goal is to see if disease progression will be further delayed by adding two different experimental injections to the standard treatment.

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URO TODAY: Researchers have discovered that prostate tumours in mice can cause immune cells known as CD8+ T cells to change to cells that suppress immune responses. READ MORE>

This finding, by researchers at the US National Cancer Institute, has important implications for the design of immune-based therapies for cancer.

Future work by this team will focus on defining the mechanisms by which  gain their suppressive functions.

“This will enhance our ability to generate more effective anti-tumor T cell responses in mice, which then might be translated to human.”

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WCVBTV5: Researchers are optimistic about Provenge, a new way of treating prostate cancer that would help the body’s own immune system to attack tumors once they have developed. Researchers at a number of institutions, including Beth Israel Deaconess Medical Center, are working on similar vaccine treatments. READ MORE>

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WatsonPROSTABLOG NZ: A leading NZ scientist has discovered a novel compound he believes will suppress the prostate cancer that is killing him.

Dr James Watson (right) – a former professor at the University of California, now back in NZ – discovered too late he has advanced cancer, so has embarked (with a fellow Kiwi scientist, who also has advanced prostate cancer) on a research project to stop his deadly disease.

He believes he has identified a treatment that will stimulate his immune system to fight the cancer, which has spread beyond his prostate.

He has decided to test the compound on himself, with the assistance of another eminent Auckland medical specialist.

His quest is driven partly by the altruism of finding a viable treatment for all men whose prostate cancer moves to a stage that defies treatment, and partly by his anger at not being diagnosed early when the disease could have been treated easily.

He saw several GPs before one offered him a PSA test, by which time his level was a lethal 987.

He and colleague Dr Richard Forster, an expert on immunology and plant biology, have set up a company to develop their discoveries.

They revealed their progress at the annual conference of the NZ Prostate Cancer Foundation in Napier.

READ MORE>

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JULY 28: PROSTABLOG NZ: When you go out into the sun and get all that beneficial Vitamin D on your skin – don’t go home and wash it off in the shower, says top NZ immunology scientist Dr Richard Forster.

Dr Forster – who is working with eminent colleague Dr Jim Watson on treatment for advanced prostate cancer that harnesses the body’s immune system – says lack of Vitamin D (from the sun) is linked to prostate cancer.

Men have more chance of contracting the disease the further away they live from the Equator.

We must get some sun exposure every day, if we can manage it, and ensure we don’t wash it off before the Vitamin D is absorbed, he told the Prostate Cancer Foundation of NZ annual conference in Napier last weekend. Absorption takes time.

Watch this website for a full report soon of what the two scientists say about avoiding and treating prostate cancer.

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JUNE 5:  US NATIONAL CANCER INSTITUTE: Treatment vaccines that boost the immune system’s response to tumours may have important clinical benefits for patients with various types of cancer, according to results from several clinical trials presented at the 2009 American Society of Clinical Oncology (ASCO) Annual Meeting in Orlando. READ MORE>

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JUNE 2; AQP: First there was surgery, then chemotherapy and radiation. Now, doctors have overcome 30 years of false starts and found success with a fourth way to fight cancer: using the body’s natural defender, the immune system. READ MORE>

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